《国际循环》:能否为我们介绍下哪些患者适合应用CCB? Myra Klienpeter:在ACCORD试验的强化降压组,更多患者应用了CCB。对于单纯收缩期高血压患者,我倾向于更多应用CCB。目前上市的单片复方制剂中,有很多含有长效CCB氨氯地平,应用这种单片复方制剂的患者能够较快地将血压降下来,有助于血压达标。
<International Circulation>: Could you extend this on what patients you would prefer to use calcium channel blockers for? Dr Myra Klienpeter: In the intensive therapy of the ACCORD trial there was more calcium channel blocker usage. In those patients with isolated systolic hypertension I tend to use more calcium channel blockers. A lot of the combination medication being brought into the market in which long standing calcium channel blocker amlodipine is added to the drug and those patients are able to achieve a low blood pressure in a relatively rapid fashion and help them reach their blood pressure goals.
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